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Medisinbytte gjelder både for forhåndsgodkjente legemidler og for legemidler som det gis stønad til etter individuell stønad. Noen antidepressiva kan også benyttes for søvnfremmende effekt, noen typer antidepressiva har denne egenskapen. Graviditet og amming. Hvorvidt gentleman skal bruke medisin eller ikke under svangerskapet må drøftes